"Religion makes a virtue out of not thinking, and that is nothing to brag about." - Bill Maher
At any rate, Bill Maher approaches it from a rather sanctimonious standpoint. He can be kind of adversarial at times, and relishes in making some of the people he talks to look like idiots (not that it takes much work for some of these people).
It's a good movie and raises many many good points. Particularly the paradox of religion both at once predicting the end of the world and being the single largest driving force pushing us towards the said end of world.
What I found VERY interesting, and unexpected, is the only two people he interviewed that made any sort of sense whatsoever were the two Catholic priests. However, I think the second one must have been dipping into the sacramental wine, because he either had early stages of Parkinson's or was ripped off his ass.