Thanks for the responses.
Poutanen - my stance angle is +15/-3. On my previous board (151cm Ride Decade 06/07), my stance width was just slightly over 20", with both bindings mounted on the default ref point. And yes, I slide the bindings one notch toward the toeside, so I won't be able to make lateral micro adjustment as you suggested.
I was just wondering if a larger setback would translate into more difficult turn inititation. But I'll give each setting a try next time I go up... can't wait!