try and find a super-thin liner sock made from silk or polypro to wear inside your smartwools first.
dress socks can work well. the liner helps more with wicking and also helps a ton with the slipping.
the other thing is if you're on the end of the size range, size down... IE;
ADULT SOCKS (shoe size reference)
Sizes US Men US Women Euro UK
Small 3-5.5 4-6.5 34-37 2-4.5
Medium 6-8.5 7-9.5 38-41 5-7.5
Large 9-11.5 10-12.5 42-45 8-10.5
X Large 12-14.5 N/A 46-49 11-13.5
if you're a size 9/9.5/10 get mediums
another trick for hotspots and blisters is duct tape or moleskin on your skin covering the affected area