Hey, my thigh's are 30", my waist is 38" & my inseam is 34". I wear Burton pants in XXL & I need to tighten the velcro straps, they are huge, I'm not much smaller than you & I thinkj they would still be baggy on you.
I would try on a pair of burton's at a store if you can. WIth a 42" waist it is iffy, they tend to run small. I'm not sure on the thigh part, but I have a pair of Ride Phinney's and they are good for size. I wear a 42" inch waist currently. I don't have the football build, just overweight currently and working on getting smaller. You can also try some of the columbia pants out there, they tend to run larger with sizes. Unfortunately, the snowboard brands are limited for bigger guys.