I assume many people skipped-over this because of the DVR Subject line. WTF?
As for the drive, it is very doable at night. You'd be looking at about 2 hours, maybe a little less since traffic will be non-existant. Just nap on the flight because once you land and drive up there, you be tweaking with excitement and that'll make it difficult to fall asleep. Expect a slightly groggy first day.
Depending on where you go, it is all or mostly Interstate. There can be pile-up accidents if the weather is bad, but they work hard to keep that thoroughfare (I70) open. You should be fine.
Traveling the States and Taking Pictures