defininitely E Hastings and Main
First trip to Whistler/Vancouver my 1st year of college in WA, was told to go to "Hastings street" to find the Volcano Lounge and other green friendly 420 shops... stopped in Chinatown for a quick bite, then walked North to find out fortune. Walked the ENTIRE length of east hastings, had guys just walking up to us pouring all sorts of crystals, powders, pills and whatnot in theirs hands trying to get us to buy something... walked by an alley with more bums than I had ever seen in one place in one time... all hanging of fire escapes and shit.. then finally made it to West Hastings and our green salvation! Success! I'm from a small town in Maine and that shit was UNREAL.