The Durango way is nice, but Wolf Creek Pass closes a lot more than you think. With the heavy snowfall they are talking about it will likely be closed at the ski area or at the Summit if you don't get there in time. There is a serious avalanche path on the West side and it's a monster. CDOT gets rightfully nervous about that one. Overall though, Wolf Creek pass is an easy drive if it's open. On top of all of that you got Coal Bank and Molass Pass to deal with getting into Silverton. Which I remember as being fairly gnarly in winter. Plus the extra 2-3 hours of driving going around that way.
Red Mountain Pass will get your attention, but I don't personally think it's worth avoiding because of that. I've driven over it a few times in snowy conditions, last time in a pretty good storm. Doing it in daylight if you can does help.