Well, from what I've heard it's just a matter of trading speed for inconvenience. Obviously the BOA and other systems are much faster, but occasionally have problems, though I know some don't at all. Lacing on the other hand, is pretty problem free, but it's much slower and takes more effort.
If you wan't something you can always rely on and don't mind lacing, just get some regular boots, (they tend to be cheaper too). If lacing bugs the hell out of you and you want something faster, grab some BOA. I've never used BOA's so I can't personally say anything about their reliability.
PowderHound and TreeNinja