you can get altitude sickness in tahoe. I live at about 400 ft above sea level and have experienced altitude sickness when in Tahoe...I usually don't, but it has happened a couple times.
I think the trick is to travel up there slow (and hydrate). The times I felt sick was when I drove up the mtns as fast possible. However, it's not like colorado (where I physically hurled right when I got there and felt worse than death for 4 hours later), but tahoe is high enough to feel pretty bad if you don't do it right.